The Waste Management System is a mobile waste disposal station that uses air flow to help control airborne particulate generated when disposing of cage bedding and animal waste. It also provides reduced exposure for lab personnel when waste materials are sealed for removal. Air enters the work opening of the unit and passes over the disposal ports, capturing particulate generated by emptying cages. The air is then pulled through a two-stage pre-filter system, passes through the third-stage HEPA filter (99.99% efficient to 0.3 micron particles) and is returned into the room at the rear base of the unit. Bedding and animal waste pass through funnel-shaped ports where it is channeled into dual plastic lined bags or polyvinyl-lined burn boxes. The bags or boxes are sealed in the unit before removal from the system.